Onkologie. 2026:20(3):163-168 | DOI: 10.36290/xon.2026.030

Multidisciplinary collaboration in radioligand therapy of prostate cancer

Otakar Čapoun1, Martin Matějů2, Stanislav Hloušek2, Vladimír Černý3, Petr Hanuš3, Iva Macová3, Václav Ptáčník4, Peter Papp4, David Zogala4
1 Urologická klinika, 1. LF UK a VFN, Praha
2 Onkologická klinika, 1. LF UK a VFN, Praha
3 Radiodiagnostická klinika, 1. LF UK a VFN, Praha
4 Ústav nukleární medicíny, 1. LF UK a VFN, Praha

Radioligand therapy (RLT) targeting the prostate-specific membrane antigen (PSMA) represents a significant advance in the treatment of metastatic castration-resistant prostate cancer. The implementation of this modality into clinical practice places high demands on appropriate patient selection, organizational support, and the safe delivery of treatment. This article summarizes the role of the multidisciplinary team (MDT) in PSMA-targeted RLT for prostate cancer and outlines the key responsibilities of individual specialists, including the clinical oncologist, urologist, nuclear medicine physician, radiologist, and specialized nurse. Particular attention is paid to care coordination, MDT communication, and the practical aspects of the treatment day. Based on clinical experience at the General University Hospital in Prague, a functional MDT model is presented that enables the safe, effective, and seamless integration of RLT into comprehensive oncological care.

Keywords: radioligand therapy, prostate cancer, multidisciplinary team.

Accepted: June 15, 2026; Published: July 1, 2026  Show citation

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Čapoun O, Matějů M, Hloušek S, Černý V, Hanuš P, Macová I, et al.. Multidisciplinary collaboration in radioligand therapy of prostate cancer. Onkologie. 2026;20(3):163-168. doi: 10.36290/xon.2026.030.
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