Onkologie. 2024:18(4):279-282 | DOI: 10.36290/xon.2024.058

Role of Fruquintinib in metastatic colorectal cancer

Stanislav Batko
Onkologická klinika, FN Motol a 2. LF UK, Praha

The systemic treatment for metastatic colorectal cancer (mCRC) includes the use of cytostatics, targeted therapy, and immunotherapy. Neoangiogenesis blockade has been a part of mCRC treatment for two decades. Fruquintinib, a novel tyrosine kinase inhibitor targeting vascular endothelial growth factor receptor (VEGFR) 1-3 blockade, significantly improved overall survival compared to a placebo in a heavily pretreated patient population. It also comes with a favourable, well-managed side-effect profile and is now the new standard of care for fourth line therapy for mCRC.

Keywords: metastatic colorectal cancer, Fruquintinib.

Accepted: October 1, 2024; Published: October 7, 2024  Show citation

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Batko S. Role of Fruquintinib in metastatic colorectal cancer. Onkologie. 2024;18(4):279-282. doi: 10.36290/xon.2024.058.
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