Onkologie. 2023:17(5):319-322 | DOI: 10.36290/xon.2023.060

Hepatoblastoma in three siblings associated with familial adenomatous polyposis

Viera Bajčiová
Klinika dětské onkologie, Fakultní nemocnice Brno

Hepatoblastoma is the most common primary tumour of the liver in children. Genetic predisposition may be one of the causative factors. Approximately 14 % of hepatoblastomas occur as a result of familial adenomatous polyposis. We describe a case report of a family with a genetic predisposition - three out of four children tested positive for FAP, and the three children developed hepatoblastoma at a very early age. The presented family supports genetic screening of children from a FAP-positive family at the age of 6 months to 1 year with subsequent surveillance.

Keywords: genetic syndromes, hepatoblastoma, familial adenomatous polyposis.

Accepted: November 28, 2023; Published: November 29, 2023  Show citation

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Bajčiová V. Hepatoblastoma in three siblings associated with familial adenomatous polyposis. Onkologie. 2023;17(5):319-322. doi: 10.36290/xon.2023.060.
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