Onkologie. 2015:9(2):82-84

Liver metastases, the role of interventional radiology

Vlastimil Válek¹, Tomáš Andrašina¹, Igor Kiss², Lenka Ostřížková³

¹ Radiologická klinika FN Brno a LF MU v Brně

² Klinika komplexní onkologické péče MOU Brno a LF MU v Brně

³ Interní hematologická a onkologická klinika FN Brno a LF MU v Brně

Unresectable colorectal liver metastases have a 1- and 2-year survival of 55 % and 33 % with current systemic therapies. Currently image-

-guided liver-directed therapy like trans-arterial chemoembolization (TACE), hepatic arterial infusion (HAI) and termoablation (RFA) has

a growing role in the therapy of patients with liver metastases. Endovascular and percutaneous hepatic-directed therapy offers the dual

benefit of true local neoplastic control and reduction of sideeffects. The development of new embolizing agents, such as DC beads (DEB)

loaded with doxorubicin and irinotecan, permits better standardization and definition of protocols, making the procedures less linked

to criteria of different hospitals and personal experiences of interventional radiologists.

Keywords: drug-eluting beads, RFA, microwaves, liver metastases, chemoembolization, DEBIRI, colorectal cancer, liver-directed therapy

Published: April 10, 2015  Show citation