Onkologie. 2008:2(2):117-121

THE ROLE OF BRONCHOALVEOLAR LAVAGE IN THE DIAGNOSIS OF ALVEOLAR PNEUMOPATHY IN PEDIATRIC ONKOLOGY

Viera Bajčiová
Klinika dětské onkologie LF MU a FN, Brno

Pulmonary complications and infiltrates of various aetiology are the most frequent and urgent clinical problem in pediatric cancer patients. Bronchoalveolar lavage is a routine method in adult population, on the other hand the explicit recommendations for indication and methodology of bronchoalveolar lavage in childhood does not exist. Only limited literature informations exist about BAL in children, usualy designed as retrospective studies. Therefore selection criteria and methodology of bronchoalveolar lavage depending on age are need to be established, as well as standardised methods of bronchoalveolar fluid analysis. Exact and correct interpretation of results is crucial.

Keywords: pediatric oncology, pulmonary infiltrates, bronchoalveolar lavage, indications, methodology, evaluation

Published: August 1, 2008  Show citation

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Bajčiová V. THE ROLE OF BRONCHOALVEOLAR LAVAGE IN THE DIAGNOSIS OF ALVEOLAR PNEUMOPATHY IN PEDIATRIC ONKOLOGY. Onkologie. 2008;2(2):117-121.
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    References

    1. Midulla F, de Blic J, Barbato A, Bush A. et al. Flexible endoscopy of paediatric airways. Eur Respir Journal 2003; 22: 698-708. Go to original source... Go to PubMed...
    2. Nicolai T. Pediatric brochoscopy, state of the art Pediatr Pulmonology 2001; 31: 150-164. Go to original source...
    3. Stokes DC, Shenep JL, Parham D, Bozeman PM et al. Role of flexible bronchoscopy in the diagnosis of pulmonary infiltrates in pediatric patients with cancer J Pediatr 1989; 115: 561-567. Go to original source... Go to PubMed...
    4. Armenian SH, La Via Wv, Siegel SE, Mascarenhas L. Evalution of persistent pulmonary infiltrates in pediatric oncology patiens. Pediatr Blood Cancer 2007; 48(2): 165-172. Go to original source... Go to PubMed...
    5. Gruson D, Hilbert G, Valentino R. et al. Utility of fiberoptic bronchoscopy in neutropenic patients admitted to the intensive care unit with pulmonary infiltrates. Crit Care Med 2000; 28(7): 2224-2230. Go to original source... Go to PubMed...
    6. Paiva MA, Amaral SM. Chronic interstitial lung diseases in children J Pediatr (Rio J) 2007; 83(3): 233-240. Go to original source... Go to PubMed...
    7. Balfour-Lynn IM, Spencer H. Bronchoscopy - how and when? Pediatr Respir Reviews 2002; 3: 255-264. Go to original source... Go to PubMed...
    8. Swaminathan S, Vijayasekaran D, Somu N: Bronchoalveolar lavage in pediatrics Indian J Pediatr 1996; 63: 163-169. Go to original source... Go to PubMed...
    9. Rosenthal M. Bronchoscopy and infection. Paediatr Respir Rev 2003; 4(2): 143-146. Go to original source... Go to PubMed...
    10. Kabra SK, Bhargava S, Lodha R et al. idiopathic pulmonary hemosiderosis.Clinical profile and follow up of 26 children. Indian Pediatr 2007; 44(5): 333-338. Go to PubMed...
    11. Sihoe AD, Ng VM, Liu RW et al. Pulmonary alveolar proteinosis in extremis: the case for aggressive whole lung lavage with extracorporeal membrane oxygenation support. Heart Lung Circ 2007; 3. Go to original source... Go to PubMed...
    12. Salih ZN, Akhter A, Akhter J. Specificity and sensitivity of hemosiderin-laden macrophages in routine bronchoalveolaar lavage in chcildren. Arch Pathol Lab Med 2006; 130(11): 1684-1686. Go to original source...
    13. Hilliard TN, Sukhani S, Francis J et al. Bronchoscopy following diagnosis with cystic fibrosis. Arch Dis Child 2006; 6.
    14. Ceruti M, Rodi G, Stella GM et al. Successful whole lung lavage in pulmonary alveolar proteinosis secondary to lysinuric protein intolerance: a case report Orphanet J Rare Diseases 2007; 2: 14-20. Go to original source... Go to PubMed...
    15. Efrati O, Gonik U, Bielorai B et al. Fiberoptic bronchoscopy and bronchoalveolar lavage for the evaluation of pulmonary diseases in children with primary immunodeficiency and cancor. Pediatr Blood Cancer 2007; 48(3): 324-329. Go to original source... Go to PubMed...
    16. Meyer S, Reinhard H, Gottschling S et al. Pulmonary dysfunction in pediatric oncology patiens. Pediatr Hematol Oncol 2004; 21(2): 175-195. Go to original source... Go to PubMed...
    17. Eikenberry M, Bartakova H, Defor T et al: Natural history of pulmonary complications in children after bone marrow transplantation. Biol Blood Marrow Transpant 2005; 11(1): 56-64. Go to original source... Go to PubMed...
    18. Vega-Briceno LE, Holmgren NL, Bertrand P et al: utility of bronchoalveolar lavage in immunocompromised children: diagnostic yeld and complications. Arch Bronchopneumol 2004; 40(12): 570 - 574. Go to original source... Go to PubMed...
    19. Park JR, Fogarty S, Brogan TV: Clinical utility of bronchoalveolar lavage in pediatric cancer patiens. Med Pediatr Oncol 2002; 39(3): 175-180. Go to original source... Go to PubMed...
    20. Ratjen F: Reference values for bronchoalveolar lavage in children. Monaldi Arch Chest Dis 2000; 55(3): 247-250. Go to PubMed...
    21. Ahrens P, Zielen S, Kitz R et al: Differential cytology of bronchoalveolar lavage fluid in healthy children in comparison with children colonized by lung-specific pathogens. Pneumologie 1997; 51(2): 99-103. Go to PubMed...
    22. Riedler J, Grigg J, Stone C et al: bronchoalveolar lavage cellularity in healthy Children. Am J Respir Crit Care Med 1995; 152(1): 163-168. Go to original source... Go to PubMed...
    23. Ratjen F, Bredendiek M, Brendel M et al: Differential cytology of bronchoalveolar lavage fluid in normal children. Eur Respir J 1994; 7: 1865-1870. Go to original source... Go to PubMed...
    24. Apibal S, Charoenpan P, Saenghirunvattana S et al. Cell analysis of bronchoalveolar lavage. J Med Assoc Thai 1995; 78(12): 678-684. Go to PubMed...
    25. Young JA, Hopkin JM, Cuthbertson WP. Pulmonary infiltrates in immunocompromised patients: diagnosis by cytological examination of bronchalveolar lavage fluid. J Clin Pathol 1984; 37: 390-397. Go to original source... Go to PubMed...
    26. Buchheidt D, Baaust C, Skladny H et al. Clinical evaluation of a polymerase chain reaction assay to detect Aspergillus species in bronchoalveolar lavage samples of neutropenic patiens. British J Haematol 2002; 116: 803-811. Go to original source... Go to PubMed...

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