Onkologie. 2007:1(1):39

Exemestan zlepšuje výsledky adjuvantní léčby hormon-dependentního karcinomu mléčné žlázy u postmenopauzálních žen

Jaroslav Němec
Kuwait Cancer Control Center, Medical Oncology

Podle interview s hlavním řešitelem studie, Dr. R. C. Coombsem - Multicentrická randomizovaná studie IES (Intergroup Exemestane Study) prokázala, že sekvenční podání selektivního inhibitoru aromatázy Aromasinu (exemestan, Pfizer) po tamoxifenu u časného hormon-dependentního karcinomu prsu u postmenopauzálních žen zvyšuje naději na vyléčení. Definitivní výsledky byly prezentovány na ASCO Annual Meeting 2006...

Published: May 5, 2007  Show citation

ACS AIP APA ASA Harvard Chicago Chicago Notes IEEE ISO690 MLA NLM Turabian Vancouver
Němec J. Exemestan zlepšuje výsledky adjuvantní léčby hormon-dependentního karcinomu mléčné žlázy u postmenopauzálních žen. Onkologie. 2007;1(1):39.
Download citation

References

  1. Bertelli G et al. Intergroup AROMASIN Study: Results of the Endometrial Sub-Protocol, Presented at SABCS 2004, USA.
  2. Coombes RC. A Randomized Trial of AROMASIN after Two to Three Years of Tamoxifen Therapy in Postmenopausal Women with Primary Breast Cancer. N Engl J Med. March 11, 2004. Vol. 350 No. 11. Go to original source... Go to PubMed...
  3. Coombes RC. First mature survival analysis of the Intergroup Exemestane Study: a randomised trial in disease-free, postmenopausal patients with early breast cancer randomized to continue tamoxifen or switch to exemestane following an initial 2-3 years of adjuvant tamoxifen. Abstract LBA527, presented at ASCO 2006 OR [Details of Clinical Study Report to be inserted pending availability.].
  4. Coleman RE et al. Intergroup Exemestane Study (IES): 1 years results of the bone sub-protocol. Presented at SABCS 2004, USA.
  5. Coleman RE et al. Skeletal effects of AROMASIN in the Intergroup AROMASIN Study (IES) two year bone mineral density and bone biomarker data. Presented on December 10 2005, SABCS, USA.
  6. Fallowfield LJ et al. Quality of Life in the Intergroup AROMASIN Study (IES) - a Randomized Trial of AROMASIN versus Continued Tamoxifen after 2-3 years of Tamoxifen in Postmenopausal Women with Primary Breast Cancer. Journal of Clinical Oncology. Vol 24, No 6, Feb 20, 2006. Go to original source... Go to PubMed...
  7. Lundkvist et al. Cost-effectiveness of exemestane versus tamoxifen ad adjuvant therapy for early-stage breast cancer after 2-3 years treatment with tamoxifen in Sweden. Poster 358 presented at EBCC 2006. Go to original source...
  8. Risebrough NA et al. Economic evaluation of switching to AROMASIN at 2.5 years versus continuing tamoxifen as adjuvant therapy in early breast cancer: A Canadian perspective. Poster 2060 presented at SABCS 2005.
  9. Thompson D et al. Cost-Effectiveness of Switching to AROMASIN Following Two-to-Three Years of Therapy with Tamoxifen in Postmenopausal Women with Primary Breast Cancer, Poster 5037 presented at SABCS 2005.
  10. Wordsworth et al. Exemestane in adjuvant treatment of early-stage breast cancer in postmenopausal women: results of a UK cost-effectiveness model, Poster 354 presented at EBCC 2006.




Oncology

Madam, Sir,
please be aware that the website on which you intend to enter, not the general public because it contains technical information about medicines, including advertisements relating to medicinal products. This information and communication professionals are solely under §2 of the Act n.40/1995 Coll. Is active persons authorized to prescribe or supply (hereinafter expert).
Take note that if you are not an expert, you run the risk of danger to their health or the health of other persons, if you the obtained information improperly understood or interpreted, and especially advertising which may be part of this site, or whether you used it for self-diagnosis or medical treatment, whether in relation to each other in person or in relation to others.

I declare:

  1. that I have met the above instruction
  2. I'm an expert within the meaning of the Act n.40/1995 Coll. the regulation of advertising, as amended, and I am aware of the risks that would be a person other than the expert input to these sites exhibited


No

Yes

If your statement is not true, please be aware
that brings the risk of danger to their health or the health of others.