Onkologie – 2/2023

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Available from: http://www.ncbi.nlm. nih.gov/pubmed/24489105. 29. Cooper ZA, Reuben A, Spencer CN, et al. Distinct clinical patterns and immune infiltrates are observed at time of progression on targeted therapy versus immune checkpoint blockade for melanoma. Oncoimmunology. 2016;5(3). 30. Pieper N, Zaremba A, Leonardelli S, et al. Evolution of melanoma cross-resistance to CD8+ T cells and MAPK inhibition in the course of BRAFi treatment. Oncoimmunology [Internet]. 2018 Aug 3 [cited 2020 Feb 29];7(8):e1450127. Available from: http://www.ncbi.nlm. nih.gov/pubmed/30221038. 31. Jiang X, Zhou J, Giobbie-Hurder A, et al. The activation of MAPK in melanoma cells resistant to BRAF inhibition promotes PD-L1 expression that is reversible by MEK and PI3K inhibition. Clin Cancer Res. 2013;19(3):598-609. 32. Liu L, Mayes PA, Eastman S, et al. The BRAF and MEK Inhibitors Dabrafenib and Trametinib: Effects on Immune Function and in Combination with Immunomodulatory Antibodies Targeting PD-1, PD-L1, and CTLA-4. Clin Cancer Res [Internet]. 2015 Apr 1 [cited 2023 Mar 19];21(7):1639-1651. Available from: https://pubmed.ncbi.nlm.nih.gov/25589619/. Řešením je ELEKTRONICKÉ PŘEDPLATNÉ Chcete číst aktuální články časopisu ONKOLOGIEON-LINE? ◼ www.onkologiecs.cz ČTĚTE IHNEDv podobě listovačky či ve formátu PDF ◼ bez přihlášení/předplatného jsou články přístupné až po 1 roce ◼ 5 čísel/rok – 660 Kč (vč. tematických příloh) Objednávejte v našem e-shopu➜ www.solen.cz

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